The concomitant utilization of TYLENOL® with Codeine with all CYP3A4 inducers or discontinuation of the CYP3A4 inhibitor may possibly end in lower codeine concentrations, increased norcodeine degrees, and fewer metabolism via CYP2D6 with resultant reduce morphine levels. Chilly, clammy pores and skin dry mouth fainting no hypertension or pulse